Recently, the old driver Durex can be said to have earned enough attention. Especially on the day of Thanksgiving, starting from 10:00 am until the end of 10:00 pm, Durex released a poster every hour, still a simple composition, dirty copy, smashed Green Arrow, Dove, Snickers, There are more than a dozen brands such as the beautiful old vinegar in Shanxi. But what we are discussing today is the subdivided silicone application field represented by Durex, Okamoto, etc. in the field of medical and health.
 
The development of family planning supplies in China has experienced a long development stage. From the initial talcum powder to the use of methyl silicone oil as a lubricant in the 1980s, it can be said that the development of family planning supplies is closely related to the development of China's silicone industry. For methyl silicone oil, most non-industry people, even if they have used condoms, are still quite a strange word. Methyl silicone oil is not oil. It is a linear organosiloxane polymer, commonly known as silicone oil. Under normal circumstances, methyl silicone oil is non-toxic, colorless, odorless, and non-volatile. It is widely used by using some related properties. In the field of health care. If it is non-toxic to the human body, good lubricity, etc., it is used as a lubricant for condoms; using its antifoaming effect, it has made oral gastrointestinal dissipative tablets, and pulmonary edema defoaming aerosols and other medicinal products. Using the anticoagulant effect of silicone oil, it can be used to treat the surface of the blood reservoir, prolonging the storage time of the blood sample; certain pastes based on silicone oil, because silicone oil increases the permeability of the drug to the skin, can be scald, dermatitis, Hemorrhoids have a good effect.
Silicone oil used in the field of health care, whether it is used for lubrication or for internal use for defoaming, needs to meet the medical standard, namely pharmaceutical grade dimethicone. The standard detailed description of the drug dimethicone is included in the 2015 Chinese Pharmacopoeia, which is summarized as follows:


Trait
This product is a colorless, clarified oily liquid; odorless or almost odorless;
Relative density The relative density of this product (General Rule 0601) is 0.960~0.980g/cm3;
Refractive index The refractive index of this product (General Rule 0622) is 1.4020~1.4040.
Viscosity The kinematic viscosity of this product at 25 ° C (General rule 0633 first method of capillary method, capillary inner diameter of 2mm; viscosity of 1000mm2 / s and above using the second method of rotational viscometer method).




"identification"
Take 0.5g of this product, add 0.5ml of sulfuric acid and 0.5ml of nitric acid, slowly ignite, that is, form white fiber, and finally leave white residue.




"an examination"
Acid and alkali ethanol and chloroform 5ml each, shake well, add 1 drop of phenolphthalein indicator solution, add sodium hydroxide titration solution (0.02mol / L) to slightly pink, add 1.0g of this product, shake; if colorless Add sodium hydroxide titration solution (0.02mol / L) 0.15ml, should be pink; if pink, add sulfuric acid titration solution (0.01mol / L) 0.15ml, pink should disappear.
The phenyl compound was taken from 5.0 g of this product, placed in a test tube, and 10 ml of cyclohexane was precisely added, shaken to dissolve, and the absorbance was measured in the wavelength range of 250 to 270 nm by ultraviolet-visible spectrophotometry (General Rule 0401). Should not exceed 0.2.
Loss on drying Take this product and dry it at 150 °C for 3 hours. The weight loss should not exceed 0.5% (General Rule 0831).
Take 1.0g of heavy metal, place it in the colorimetric tube, add chloroform to dissolve and dilute to 20ml, add 1.02% dithizone chloroform solution 1.0ml, water 0.5ml and ammonia test solution 0.2% hydrochloric acid. 0.5 ml of a mixed solution of hydroxylamine solution (1:9) was used as a test solution. Another 20 ml of chloroform is placed in a colorimetric tube, and a freshly prepared 0.002% dithizone chloroform solution 1.0 ml, a standard lead solution 0.5 ml, and an ammonia test solution-0.2% hydroxylamine hydrochloride solution (1:9) are added. 0.5 ml of the mixed solution was used as a control solution. Immediately and vigorously shake the test solution and the control solution for 1 minute, the red color produced by the test solution is not deeper (0.0005%) than the control solution.


China's current high-end applications such as medical and health, food, transformer oil, etc., are basically monopolized by foreign brands such as Dow Corning and Wacker. Yichang Kelin is positioned as an excellent supplier of high-purity silicone oil in the world. It obtained the food-grade silicone oil production license in 2016. It is the first company in China to obtain this license. It is the first to break the monopoly position of foreign brands in the food field, making domestic silicone oil. There is a place in the food field, I believe that in the near future, Yichang Colin will also be seen in other high-end areas such as health care.