Dracaena Draconis is the resin of Dracaena Dracaena in Liliaceae, mainly distributed in Yunnan, Guangxi, Hainan and Southeast Asia. Dragon's blood is warm, flat, sweet and salty, nontoxic, and can be divided into three meridians: lung, spleen and kidney. It has the remarkable effects of activating blood circulation and removing blood stasis, detumescence and pain, astringent and hemostasis, soft and hard, resolving knots, generating muscles and accumulating sores. In recent years, with the influx of rural labor into the city, Dracaena Draconis trees have become the mainstay of urban construction, resulting in the decline of the number of resin harvesting year by year, the growing cost of harvesting, and the output has been unsatisfactory. In the long run, the rising momentum of the product will not be reduced, and the future market will continue to maintain high-level operation. Flow cytometry was used to analyze the cell cycle changes of keratinocytes under the optimal concentration of culture conditions, and to promote the proliferation of keratinocytes.
In recent years, the country's efforts to protect the environment have increased year by year, and some small and medium-sized enterprises with high energy consumption and high pollution have been shut down for rectification, which leads to a direct reduction of dragon's blood production. Aftermarket analysis: in recent years, with the increase of investment in research and development, the new efficacy of dragon's blood has been found, and the types of drugs, health products and drinks produced according to its main drug have been increasing. At present, science and technology of Dracaena Draconis can not increase its output by artificial synthesis. With the increasing demand, the emergence of favorable factors of production reduction and the intervention of social idle funds. The effect of dragon's blood extract on the proliferation of keratinocytes in vitro. The publication and implementation of the national new pharmacopoeia of Dracaena Draconis also made some manufacturers' substandard sources of goods rejected by the sales terminals.
Under the influence of international relations, the import and export of Chinese herbal medicines are strictly controlled by the customs, and the supply of some Chinese herbal medicines produced by neighboring countries cannot smoothly supplement the domestic market; in addition, affected by the global El Ni? O phenomenon, some countries and regions suffer from different degrees of drought or waterlogging, which has a very obvious impact on the market of most of these kinds of Chinese herbal medicines. On the other hand, after the continuous digestion of the stock of these Chinese herbal medicines in the domestic market, the contradiction between supply and demand is gradually emerging, and the psychology of the audience is further promoted. On the whole, it is still relatively strong; if the Customs control continues to be tight in the later period, the price of this kind of varieties may still continue to rise. The researchers obtained three kinds of extracts from Draco Draconis by reflux extraction of chloroform, ethyl acetate and ethanol, and cultured the keratinocytes. The effects of different extracts of Draco Draconis on the proliferation of keratinocytes in vitro at different concentrations and different time points, and drew the cell growth curve at the optimum concentration. Draco Draconis has the effects on the migration and proliferation of keratinocytes in the process of re epithelialization Significant promoting effect.
Dragon's blood comes from more than 10 kinds of resinous traditional Chinese medicine of the tropical Palmae, rattan and Liliaceae, which has complex components, mainly including flavonoids such as dragon's blood, dragon's blood and triterpenoids. At present, the clinical application of dragon's blood and muscle growth drugs containing dragon's blood in the treatment of refractory wounds has definite curative effect, but its mechanism is not clear The previous studies mainly focused on the aspects of promoting blood stasis and improving blood supply of wound, but could not fully explain the mechanism of promoting wound healing. Epidermis covering is the key step of wound healing, and keratinocytes account for 90% of the epidermis.
In recent years, with the influx of rural labor into the city, Dracaena Draconis trees have become the mainstay of urban construction, resulting in the decline of the number of resin harvesting year by year, the growing cost of harvesting, and the output has been unsatisfactory. In recent years, the country's efforts to protect the environment have been increasing year by year, and some small and medium-sized enterprises with high energy consumption and high pollution have been shut down for rectification, resulting in a direct reduction in dragon's blood production. Wound healing of Dracaena Draconis needs three processes: wound contraction, granulation tissue filling and re epithelialization; re epithelialization generally needs to go through the processes of keratinocyte activation, migration, proliferation and basement membrane repair, etc. speeding up the proliferation of keratinocytes can shorten the re epithelization process in wound healing. It has been found that dragon 's blood can promote the migration of keratinocytes. The ethyl acetate extract of Draconis Draconis can promote the proliferation of keratinocytes.
Dragon's blood as a raw material has been developed and utilized constantly; there is still a certain amount of market stock, the recent market continues to be strong, and the price will be stable in the short term affected by the epidemic.
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