The behavior of the drop in the condensate may include spreading, droplet formation, and mixing. Generally, the liquid with small surface tension is put into the liquid with large surface tension, and the surface will spread, otherwise it is easy to form droplets. Dimethyl silicone oil is one of the common water-soluble drip pill condensants with the least surface energy (liquid paraffin 0.035N/m, vegetable oil 0.035N/m, dimethylsilicone oil 0.021N /m).
The other there are many kinds of dimethyl silicone oil specifications, can adjust the temperature and choose different models of dimethyl silicone oil, to adjust the droplets in the condensing agent forming and deposition rate, in order to achieve the best technology and quality conditions, and there is no pollution of petrochemical products with toxic substances and water dropping water discoloration mildew hidden trouble, there is no guarantee that this is liquid paraffin and vegetable oil.
Especially with S-40(polyoxyethylene monostearic acid), poloxamer as the matrix drop pills must use dimethyl silicone oil as condensate, can not use liquid paraffin as condensate, because the two base silicone oil can increase the solubility of water insoluble active drugs, is conducive to the absorption of drugs; Because of the moisture - absorbing properties of poloxamer, liquid paraffin can not be used as condensate. (Periodic treatment technology of dimethylsilicone oil in drop pill production; Due to the high price of dimethylsilicone oil, it should be recycled as far as possible in production. The used dimethylsilicone oil will be mixed with foreign bodies. One of the most common foreign bodies is the broken pills produced during the preparation of dropping pills, which can be removed by filtration, static precipitation or centrifugation. Another common foreign body for water, the use of mixed oil water dimethylsilicone oil as a condensing agent, drop pills may appear to dissolve, deformation or even can not be condensed and hardened, the method of removing the water in dimethylsilicone oil is: the bottom of the water of the dimethylsilicone oil frozen at -4℃, to be condensed into ice after the removal of water, quickly filtered, can be removed.